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Undifferentiated small cell carcinoma of the lung

Undifferentiated small cell carcinoma of the lung

Undifferentiated small cell carcinoma of the lung

Undifferentiated small cell carcinoma of the lung

 

  • Undifferentiated small cell carcinoma of the lungs is highly aggressive tumor with neuro-endocrine activity.
  • It is built by lymphocytic-like cells with scant cytoplasm or spindle shape cells resembling ‘oat grains’.
  • Their nuclei are hyperchromatic. Cells are clustered in strands, the tumor stroma is scant.
  • Immunochistochemistry: pancytokeratin, neuron-specific enolase, chomogranin positive stains.

 

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Filed in: Neoplasia

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