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Transitional cell carcinoma of urinary bladder

Transitional cell carcinoma of urinary bladder

Transitional cell carcinoma of urinary bladder

Transitional cell carcinoma of urinary bladder

 

  • Tumor occurs from the mucosa of the urinary bladder.
  • It is composed of a large number of branched papillae, covered with multilayered epithelium, often with anastomoses.
  • They are built up of tender fibro vascular ‘core’, covered with atypical urinary epithelium, which thickness  exceeds several times the normal one.
  • On the surface are found so called  ‘umbrella’ cells.
  • More differentiated forms have soft papillae and faint cell atypia.
  • In tumor progression are found abnormal mitoses and infiltration in the bladder’s wall. Papillae are short, thick and at some places are fused together.

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