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Squamous cancer of the lung

Squamous cancer of the lung

Squamous cancer of the lung

Squamous cancer of the lung

 

  • Sguamous carcinoma of the lung occurs after squamous metaplasia of cylindrical bronchial epithelium ( smoking, chronic bronchitis).
  • Tumor sprouts as anastomosing strands and nests.
  • At the periphery, are located  cells of the basal  layer, atypical polygonal spinous layer cells (SpCl) – with pink cytoplasme , showing intercellular bridges and mitoses.
  • Cell from granulosa layer of the squamous epithelium  are  sparcey presented, but in differentiated forms in the centre of nests keratin is deposited forming the so called. ‘cancer pearls.
  • Tumor infiltration in  lymph vessels is presented with stromal ‘reaction’: with lymphocytes and plasma cells, and around necrotic areas–segmented leukocytes.

 

Squamos carcinoma of the lung

Squamos carcinoma of the lung

 

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