Renal cell carcinoma – pathology and pictures
- Tumor cells with polygonal shape are arranged in nests, tubules and papillae.
- They have bright cytoplasm and well presented cell membrane. The light cytoplasm is due to extraction of lipids and glycogen from their cytoplasm.
- Tumor cells infiltrate walls of blood vessels.
- Among tumor are found necroses and hemorrhages.
- Stroma is scant, with thin-wall blood vessels and scant lymphoid infiltrations.
- Tumor is well distinguished with a pseudocapsule (PsC): thick fibrous connective tissue, which at some places appear to have neoplastic infiltration.