The three morphological signs for molar pregnancy are:
1. Extremely swollen chorionic villi - with mucoid edema, and the formation of intrachorionic ‘lakes’ (arteficial phenomenon from the technical processing of the specimen);
2. No fetal blood vessels are found in the stroma of the villi;
3. The trophoblast over villi’s surface is with signs of intense proliferation and forms the so called trophoblastic columns (budding and papillae-like formations)
The size of the uterus exceeds the size corresponding to duration of pregnancy, ultrasound examination does not establish the existence of fetus and the level of serum human choriongonadotropin is 100-fold increased.
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