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Mesangiocapillary glomerulonephritis

Mesangiocapillary glomerulonephritis

Mesangiocapillary glomerulonephritis

Mesangiocapillary glomerulonephritis

 

  • The glomeruli are enlarged, markedly  lobulated and ‘rich’ in cells due to proliferation of mesangial cells (more than 2 cells in a plane section) and accumulation of basement membrane-like material.
  • The capillary walls are thick , their lumens – narrow due to the penetration of mesangium in  between the endothelium and basement membrane (so called  ‘mesangial interposition’).
  • With silver stain, this phenomenon is seen as a duplication of basement membrane (‘tram rails’ – metaphor).

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