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Chronic peptic ulcer – pictures

Chronic peptic ulcer – pictures

Chronic peptic ulcer

Chronic peptic ulcer

  • Sharply distinct defect (2-4 cm), which destroys mucosa, penetrates the muscularis propria and even to serosa (sign for perforation).
  • Gastric glands on the edges of the defect are hypertrophic.
  • Bottom of the ulcer is covered with fibrino-purulent exudate.
  • Below comes  the ‘purple-red’ destructive area of fibrinoid necrosis.
  • Below it  - plenty of maturing granulation tissue.
  • In depth  – a sclerotic area (fibrous connective tissue), in which are found vessels with highly thickened walls – endarteriitis-like and endophlebitis-like changes (shown inset)
  • Peripheral nerve fibres are also big and hyperthrophic, the so called amputation neuroma.
  • Gastric mucosa around the ulcer is with signs of chronic atrophic gastritis.
Chronic peptic ulcer
Chronic peptic ulcer

 

 

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