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Atherosclerosis of aorta

Atherosclerosis of aorta

Atherosclerosis of aorta

Atherosclerosis of aorta

 

  • At the centre of atherosclerotic plaque ( light central area ): chaotically placed spindle-shaped in optically ‘empty’ spaces where are located ‘needle’-like cholesterol crystals. Such is the picture in deparaffinized alcohol fixed tissues.
  • Sudan ІІІ is used to prove lipids during formalin fixation of tissue and cutting with freezing microtome. Lipid deposits are stained in orange.

 

  • Replacing the endothelium and over the fibrous cap (FC) of complicated plaque is the place where mixed thrombus can be formed (MT).
  • Media is atrophic (М), and the blue line on the border with lipid deposits is dystrophic calcification .

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