Adenocarcinoma of prostate gland
- Atypical glands of prostate carcinoma are densely packed (‘back to back’) . They have irregular shape, and their basal membranes are destroyed at some places.
- Tumor glands and single cells infiltrate adjacent smooth muscle and fibrous tissue.
- In needle biopsy specimens is very important to look for perineural infiltration.
- Diagnosis can be supported with immunohistochemical reaction for prostate specific antigen (PSA).