Acute duodenal ulcer
- Acute duodenal ulcer is a mucosal defect which unlike the â€˜erosionâ€™ penetrates through muscularis mucosae to reach muscularis propria (MP).
- Glands in the area of the ulcerated edges are destroyed.
- In the edges and in the area of mucosal defect is found leukocytic inflammatory reaction.
- At the bottom of the ulcer is found hemorrhage (macroscopicallyâ€“ black color because of the transfer of hemoglobin into hematin ), cellular debris and fibrino-purulent exudate.
- The underlying duodenal layers show no fibrosis.